rat or mouse, the disease subtype of Diabetes mellitus (DM), the number of animals in this study utilized as the control group and the experimental or the DCM group, the dose, route of administration and the number of consecutive days the STZ was injected, the blood sugar cutoff point which confirms that diabetes was induced, the gender, age and bodyweight of the rodent species, and the primary outcomes reported by each included study are described in this table (Table 4)
Management focuses on identifying and treating the underlying cause rather than lowering B12 levels directly
Over 8000 varieties of polyphenols have been identified so far, each contributing to the health promotion and prevention of several diseases by virtue of their potent antioxidant, anti-inflammatory, anti-tumorigenic, anti-bacterial, as well as other biological activities
Metformin use and risk of B12 deficiency increases with the dose and the duration depletion can be seen as early as 3-4 months after starting so it is important to attend for follow up blood tests and talk to your doctor
