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This holistic approach underscores the importance of considering the intricate molecular and biophysical factors that contribute to ligament health and resilience, ultimately leading to improved outcomes for athletes and active individuals

In the case of diabetes retinopathy, the retina is damaged by retina neovascularization where new vessel origination from existing veins extends to the retinal inner cells [82] leading to blindness [83]

To evaluate the sensitivity of the two culture systems to ferroptotic cell death, we treated the four lung cancer primary cultures (BBIRE-T248, PUC30, PUC36, and PUC37) with RSL3, a ferroptosis activator with selectivity for tumor cells bearing oncogenic Ras, which acts by inhibiting the glutathione peroxidase 4 (GPX4)

J Am Chem Soc 116:74237424 Borbely A, Toth A, Edes I, Virag L, Papp JG, Varro A, Paulus WJ, van der Velden J, Stienen GJ, Papp Z (2005) Peroxynitrite-induced alpha-actinin nitration and contractile alterations in isolated human myocardial cells