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Findings were assessed across multiple independent datasets, including FinnGen, Psychiatric Genomics Consortium (PGC), and UK Biobank, and were synthesized through meta-analysis

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Docosahexaenoic diesters (DHA)-acylates synthesized from astaxanthin (AST-DHA) have shown substantially better effects than astaxanthin in reducing tau protein oxidative stress, improving learning and memory, and suppressing apoptosis of dopaminergic neurons [103, 104]