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In addition, this parameter was recorded for the study of lipid profile, considering the demonstrated role of oxidative stress, both in the induction of cardiac arrhythmias and in lipid oxidation with subsequent development of an immune response, with a pathogenic evolution towards accelerated atherosclerotic endothelial dysfunction (4)

CaMKK2 dysfunction may play an underlying role in this phenomenon as genetic deletion of Camkk2 in hippocampal neurons, myeloid cells and immortalized cell lines (HEK293 and HepG2) results in mitochondrial dysfunction that causes a similar switch in cellular energy generation from oxidative phosphorylation to glycolysis [43, 201, 202]

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Its benefits, including convenience, self-administration potential, and minimal discomfort, make it a preferred choice for certain medications and patient populations