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In some embodiments, high viscosity formulations or devices contain from about 15% to about 21% of a viscosity enhancing agent or viscosity modulating agent (e.g., gelling components such as polyoxyethylene-polyoxypropylene copolymers)

98% is considered research-grade, but 99% purity is strongly preferred for collagen synthesis assays, gene expression studies, wound healing models, and skin biology research where compound purity directly affects experimental accuracy

Meijer, E.R

Abstract The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids