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Comparison across biofluids further highlighted both opportunity and constraint: while lumbar and ventricular CSF showed strong concordance, plasma profiles diverged substantially, particularly for immune-active pathways such as kynurenine metabolism 67 , indicating that treatment-relevant metabolic states are most directly captured in CSF and only partially reflected in peripheral blood

BPC-157 has shown promising analgesic effects, providing relief from discomfort and improving patients quality of life

Eksperimentalnaia i Klinicheskaia Farmakologiia, 65 , 66-72