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Moreover, different types of PTMs do not exist in isolation but have a certain degree of interactivity and correlation, forming a potential network system of PTMs
Its pharmacokinetic profile indicates rapid absorption and widespread tissue distribution, with no evidence of significant central nervous system accumulation (Jzwiak et al
Expression of micronutrient deficiencies in ASD Frequently overlooked are the data demonstrating that endogenous aldehydes induce localized, intracellular deficiencies in a subset of micronutrients, which either initiate oxidative stress (multiple sulfur-containing antioxidants, Zn 2+ ) or serve as cofactors (B1, B6, folate, and Zn 2+ ) in the metabolic pathways implicated in autism: neurotransmitter functions, DNA methylation, chromatin remodeling, transcriptional regulation, and neuronal development
Nature 385, 533536
