The periorbital area has thin skin and delicate vascularity requiring significantly different injection depth, volume and formulation than facial mesotherapy
The limbic system is the part of the brain that includes the hippocampus and amygdala, the seat of motivation, emotion, learning, and memory
Risks may include joint pain, insulin resistance in some contexts, edema, carpal tunneltype symptoms, and potential tumor promotion in those with existing malignancies, which is why medical screening is important
Just as importantly, the symptoms patients attribute to "low GH" fatigue, poor recovery, low energy overlap heavily with hypothyroidism, depression, sleep apnea, and low testosterone, so those causes should be ruled out first