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While not classified as a controlled substance in most regions, it is not approved for human consumption and is generally restricted to research purposes
An excellent example is the pain medication ziconotide, a synthetic form of a peptide found in the venom of the marine cone snail
The Human Gene Mutation Database (HGMD) contains 43 different GSS variants that have been reported as of January 2023, with missense variants showing predominance (55.8%), followed by splice variants (21.0%), small insertions/deletions (11.5%), large insertions/deletions (7.0%), and nonsense variants (4.7%)
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