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5 Apoptotic death of the retinal ganglion cells (RGCs) has been shown 6 and, in addition, the effect of the intraocular hypertension causes a significant overexpression of caspase 3, which is a commonly accepted marker of programmed cell death

Finkelstein JD, Harris BJ, Martin JJ: Methionine metabolism in mammals: Concentrations of metabolites in rat tissues

55,56 These findings prompted regulatory safety communications and heightened surveillance regarding pancreatic safety

In other words, as a precursor of L-cysteine, which results in glutathione biosynthesis, NAC (along with glutamine and glycine) is an amino acid that is needed to produce whats arguably the most important antioxidant in the human body