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443 Lipids that accumulate during regeneration not only serve as the energy supply and substrates for membrane synthesis but also directly contribute to regulating the downstream production of metabolites to coordinate cell proliferation via transcriptional or epigenetic mechanisms

Early-stage research has demonstrated that microneedle technology can deliver peptides like semaglutide in animal models

This nanoformulation holds great promise for improving patient outcomes in diabetic retinopathy therapy

at the same time, AP-1 downregulates the expression of transforming growth factor- (TGF-) receptor type II, which disrupts the downstream Smad/TGF- signal pathway, thereby reducing the transcription of the COL1A1 and COL3A1 genes encoding type I and type III collagen (41,50-52)