Obesity and visceral adiposity are key drivers of HFpEF development and progression, and this may be even more amplified in women, who represent the majority of people with the disease, and bear a heavier burden of symptoms and physical limitations due to HFpEF, says Mikhail Kosiborod, MD, FACC, senior author of the study and a cardiologist at Saint Lukes Mid-America Heart Institute
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Decreasing inflammatory cytokines reducing markers like TNF-, CRP, and IL-6
