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Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation
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The Gila monster, which feeds infrequently and can survive for months without food, may use similar metabolic mechanisms, though the precise role of exendin-4 in the lizard's own physiology continues to be studied