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Evidence from in vitro experiments shown that AGNHP mitigated ferroptosis damage caused by erastin in PC12 cells, enhanced cell survival, decreased LPO and Fe 2+ concentrations, and boosted mRNA expressions of PPAR, AKT, and GPX4 (Bai et al., 2024)

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Notably, the hypothalamicpituitaryadrenal axis is impaired in Covid-19 patients, as reflected by low ACTH and cortisol levels

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