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Nutrient deficiencies can then lead to various disorders throughout the body

The acronym PICO stands for population (individuals with BED), intervention (administration of GLP-1 agonists in individuals with BED), comparison (individuals with BED who received a placebo, lifestyle interventions, and other medications excluding GLP-1 agonists), and outcomes (effectiveness of GLP-1 agonists, particularly about weight loss) as reported in the articles

When the distribution was normal, but the variance was unequal, we used the Welchs t-test

[18] investigated the effects of GLP-1 receptor activation on counter-regulatory hormones (i.e