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In total, 37 participants received semaglutide and 38 participants received placebo (ESM Fig

Potential Considerations Though GLP-1 medications are generally well-tolerated, some individuals may experience: Mild nausea or digestive discomfort (typically improving over time) Temporary fatigue during dose adjustment Injection site reactions Changes in taste preferences Slight risk of more serious side effects (rare) Conclusion As medical weight management evolves, GLP-1 medications stand at the forefront, offering hope to those struggling with conventional weight loss methods

Empagliflozin ameliorates diastolic dysfunction and left ventricular Fibrosis/Stiffness in nondiabetic heart failure

- Niacinamide