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As we had previously demonstrated in cell lines (16), total glutamate and glutathione levels declined in primary cortical neurons treated with acivicin (Fig

Recently, several metabolomics groups have stated that MS/MS multiple reaction monitoring MRMs of reference standard compounds should be done for biomarker verification in LC/MS metabolomics studies (Kitteringham et al

If it still won't dissolve, the compound might be compromised, or you might have an insoluble impurity

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