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ALOX12 serves as the primary gene responsible for driving ferroptosis, and its mechanism of action involves the conversion of polyunsaturated fatty acids, particularly arachidonic acid, into the bioactive lipid (12S)-hydroperoxide eicosapentaenoic acid (Zheng et al., 2020)

Abstract Glutathione (GSH), the most abundant intracellular low molecular weight thiol, has diverse physiological roles, and altered GSH status has been implicated in a number of chronic, acute, and age-related diseases, as well as the aging process itself

BPC-157 is studied for tissue repair