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However, those represent a higher functional cell pool due to necrosis of the islet core in non-vascularised isolated islets 54 , so that it is still possible to assess potential functional differences from a relatively small percentage of transduced cells
We expressed the Exendin-4-Fc fusion protein and tested its bioactivity both in vitro and in vivo in order to investigate whether this represented a potential long-acting GLP-1 receptor agonist for the treatment of T2DM
Since then, shortages have ended, and the FDA says [archived link] the non-approved compounded versions can no longer be made and sold
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