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Key Takeaways AOD-9604 acts peripherally on fat cells to promote adipocyte lipolysis whereas semaglutide acts centrally to suppress appetite and regulate metabolism

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In human case reports involving serotonergic agents, symptoms progress from agitation and confusion to autonomic instability (tachycardia, blood pressure fluctuations), severe hyperthermia above 40C, and in extreme cases, rhabdomyolysis

instead, they may help regulate the communication between them