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UVA Health's Varney, who has consulted for Eli Lilly, says not to give up on trying to get GLP-1s covered

Finding the biologically important ones is difficult because genuine peptide hormones are relatively rare and can be buried among large numbers of ordinary fragments created during normal protein processing and breakdown

The article says no documented major pharmacokinetic or pharmacodynamic interaction exists between the two, and its comparison table rates the interaction risk as low because the two are handled by separate routes

Frontiers+2PMC+2 Mitochondrial health and neuronal energy : Some studies show improved mitochondrial function, decreased dysfunction, improved neuronal metabolic reprogramming in response to insulin resistance when GLP-1 pathways are engaged