A 2024 study in the journal SLEEP tracked over 60,000 adults with wrist-worn accelerometers and found that sleep regularity is a stronger predictor of mortality risk than sleep duration (Windred et al., 2024)
Similarly, almost two-thirds of participants reported increased satiety, meaning they felt fuller sooner
People living longer with obesity may have associated comorbidity [16], involving musculoskeletal, cardiometabolic and mental health complications, with higher rates of malignancy [17], although it remains unclear the extent to which cumulative exposure to obesity impacts upon their respective clinical outcomes [18,19,20,21]
Target-trial-emulation and cohort analyses report that diabetic patients on GLP-1R agonists develop dementia and Alzheimers disease at lower rates than those on comparator antidiabetic drugs, and pooled analyses of cardiovascular-outcome trials have pointed in the same direction [9]