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(2019) 39:BSR20190673

As we highlighted above with recombinant mAbs, and as shown in historical dengue virus motherinfant data, the theoretical risk of ADE in CP prophylaxis is highest in the weeks following transfusion, when antibody serum neutralization titres fall to sub-protective levels

Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Emerick K, Antoniou A, Wanty C, Fischler B, Jacquemin E, Wali S, et al

It is secreted following nutrient ingestion, resulting in enhanced glucose-stimulated insulin secretion (GSIS) from the pancreatic -cells as well as delayed gastric emptying and enhanced satiety, making it an attractive target for the treatment of T2D and obesity 3