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Recently, uridine has been reported to rejuvenate aged human hematopoietic stem cells by upregulating the FoxO signaling pathway and inhibiting inflammation 19
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The level of CAMKK2 gene expression in human brain is low during early development, but expression levels markedly increase during late childhood/early adulthood which, notably, coincides with the average age-of-onset of bipolar disorder [38, 39]
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