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Figure 1 2 Review methodology To carry out this updated review on the anticancer effects of bromelain, published studies were searched in specialized databases such as PubMed/MedLine, TRIP database, GeenMedical, Scopus, Web of Science and Google Scholar, using the next MeSH terms: Animals, Anticarcinogenic Agents/pharmacology, Antineoplastic Agents/pharmacology, Bromelain/pharmacology, Bromelain/administration and dosage, Bromelain/chemistry, Cell Line, Tumor, Cell Survival/drug effects, Dose-Response Relationship, Drug, Humans, Nanocapsules/administration and dosage, Neoplasms/drug therapy, Neoplasms, Experimental/pathology, Signal Transduction/drug effects, Treatment Outcome

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