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Methods Experimental model and details Animal studies All animal studies were performed according to protocols approved by the University Committee on Animal Resources at the University of Rochester Medical Center

Transitioning Medicare coverage of GLP-1s for obesity from the mandatory Medicare GLP-1 Bridge to the voluntary BALANCE model sets up the possibility that beneficiaries with coverage under the short-term program may need to switch Part D plans during the 2027 open enrollment period, with potential cost and coverage implications for other medications they use.

The Lenti-X 293 T cell line was obtained from Clontech Laboratories (Palo Alto, CA, USA)

Degraded medication may reduce or eliminate therapeutic effect while appearing normal