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doi: 10.1186/s12935-024-03360-y 124 WangYHongZSongJZhongPLinL

Even low-grade leakage of endotoxin (LPS) from the gut can trigger chronic neuroinflammation: LPS in the bloodstream has been shown to activate microglia in the brain via TLR4/NF-B signaling, thereby contributing to neuronal injury [37]

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Most data comes from: That said, Dihexa is being used off-label in clinical practices, and practitioners continue to monitor real-world outcomes in: Despite promising data, Dihexa has not yet completed the rigorous phases needed for FDA approval