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RESULTS Liver lesions and biochemistry assessment In controls, the grading system used to microscopically measure the extent of liver damage (the same for steatosis, necrosis, and congestion) showed no lesion presentation at the earliest point of 25 minutes after paracetamol ( Table 1 ), but liver enzymes and ammonium serum values were already increased ( Table 2 )

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The table lists nausea of any grade at 25 to 48 percent in the SUSTAIN trials for semaglutide and 25 to 50 percent in the SURMOUNT trials for tirzepatide, calling both dose-dependent and typically resolving within four to eight weeks