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This remarkable diversity of inhibitory neurons opens up an opportunity to address both cell-type and connection-specificity of plasticity rules as well as to distill basic rules common for all plastic synapses

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Moreover, increased oxidative stress and immune activation correlating with disease progression were demonstrated in serum and CSF of sporadic ALS patients [98]

In addition, these studies suggested that these peptides may modulate food intake, cardiac tone, and sleep through apparently specific receptor agonistic action