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The drug combines active ingredients semaglutide and amylin analog cargrilintide, and has been touted as a direct competitor of Eli Lillys Zepbound, which uses tirzepatide

It is frequently used in studies examining redox balance, cellular protection, and how biological systems respond to environmental stressors

That fragment acts on a target the same Washington State group helped pin down: the so-called AT4 receptor, which was identified as IRAP, insulin-regulated aminopeptidase, an enzyme rather than a classical receptor (Albiston et al., J Biol Chem 2001)