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doi: 10.3389/fcell.2022.832356

One night, I was in London in a hotel trying to get some sleep

Finally, we evaluated only the EZH2 and H3K27me3 proteins and not EZH2 and H3K27me3 mRNAs in cells exposed to cigarette smoke, since as previously showed 17 , this methodological approach seems to be adequate to define the epigenetic modifications of DAB2IP gene, by the action of methyl transferase EZH2 on H3K27 trimethylation in lysine 27

Despite these unfortunate findings, The encouraging news is that once you stop smoking, the majority of DNA methylation signals return to never-smoker levels after five years, says Roby Joehanes of Harvard Medical School and lead author on this study