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The function of NRF2 is ubiquitously conserved across different cell types, but it is widely expressed in the central nervous system (CNS), where it regulates a range of functions including redox balance, xenobiotic metabolism, inflammation, and proteostasis (Cuadrado 2022)

In addition, there is the risk of inappropriate prescribing

Administration Route by Peptide Type When Injectable GHK-CU Makes Sense The injectable form provides systemic benefits that topical cannot achieve: Whole-body tissue regeneration effects Internal organ support Consistent blood levels Better bioavailability Combined with other injectable peptides When Topical Makes Sense Topical application excels for: Targeted skin treatment Hair and scalp applications Those avoiding injections Combination with skincare routines Localized wound healing For maximum benefit, some protocols use both injectable GHK-CU for systemic effects and topical copper peptides for targeted skin benefits

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