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Direct antioxidant and protective effect of estradiol on isolated mitochondria
Figure 4 8 Translational outlook: analogs, safety liabilities, and delivery strategies Erastin has demonstrated antitumor activity in several malignancies, including gastric and colorectal cancer (69, 70), and the inflammatory, iron-loaded, oxidative microenvironment shared by many tumors and EMS provides a coherent theoretical basis for applying this strategy to EMS (71, 72)
They appear to have other benefits in the body as well, such as a positive impact on the heart, kidneys, and liver
Copenhagen: Novo Nordisk (2026)
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