what happens when you come off semaglutide The Pros and Cons of for Weight Loss Semaglutide Discontinuation and Its Health

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The most common typically strongest in the first 48 weeks as the body adapts include: Nausea (most common, usually dose-dependent) Diarrhoea or constipation Fatigue , especially during dose escalations Mild headache Reflux and acid reflux Loss of appetite (this is the therapeutic effect, not a side effect, but it can be uncomfortable) Less common but more serious effects warranting immediate physician review include pancreatitis, gallbladder disease, and kidney issues, particularly in patients with pre-existing conditions

When results slow or plateau Some people experience their first plateau during this window, where weight loss stalls for two to three weeks despite consistent medication use and dietary adherence

T., Li, H