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For most scientific analyses, it is frowned upon to dive into the data searching for any significant association-such an approach may be derided with scathing-for-academia names such as fishing expeditions, data mining, and p-hacking. But why is fishing for significant results a bad idea

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EXAMINE showed a slight, but non-significant decrease in HF related hospitalization, while SAVOR-TIMI53 showed an increase in HF hospitalization with DPP-4i use