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Key Points Glucocorticoids modulate growth hormone (GH) secretion at both the hypothalamic and pituitary level Hypoadrenalism might cause GH deficiency that is reversible during glucocorticoid replacement therapy Testing for GH deficiency in patients with hypopituitarism should always be performed after adequate periods of cortisol replacement Chronic excess of glucocorticoids, either exogenous or endogenous, causes GH deficiency that might be involved in metabolic and cardiovascular complications Treatment with recombinant GH could be considered in children and adults with glucocorticoid-induced GH deficiency This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $189.00 per year only $15.75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

The innovative LIPerfection active ingredient helps support the natural definition of the lips by encouraging microcirculation, promoting a fuller and more contoured appearance over time

conservative approach is to avoid co-administration Guideline support / no major guideline addresses this combination Why This Interaction Matters Apixaban is the most prescribed direct oral anticoagulant (DOAC) in the United States, with over 28 million dispensed prescriptions in 2023 according to FDA postmarket data