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These OA FLS express GATA binding protein 4 ( GATA4 ), a regulator of cellular senescence, which is linked to increased expression of p16INK4a , p21 and a SASP

Statistical analysis The results are presented as mean SD from at least three independent biological replicates, with all analyses performed using GraphPad Prism 7 (GraphPad Software, USA)

So, in the context of glutathione, the reduced form is referring to cysteines sulfur atom keeping its electrons to itself (Figure 2)